Metisafe® isolators are contamination-proof and particle-free workstations for aseptic applications in the pharma industry. Material transferring into work chamber is accomplished by leakproof gloves assembled at front panel ports through interlocked mechanism dynamic pass-box. Metisafe isolators are equipped with full automatic decontamination system which provides pre or post-operation sterility of air contact surfaces. The controlled aseptic environment is achieved by all of those physical and air barrier mechanisms and automatic decontamination to be used in sterility tests. Depending on the hazard level of work materials isolators are classified as positive or negative pressured cabinets.